An accidental creature born out of the T-virus outbreak at the Umbrella training facility, the Centurion started off as a simple centipede. It grew to ten meters in length and became highly aggressive. It would use its massive fangs to strike its victims and kill them. Its legs were powerful enough to grab and capture a fully grown human.

Rebecca and Billy discovered the Centurion in the training facility. The Centurion attacked without notice capturing Rebecca with its legs. Billy frantically fought the giant centipede in an effort to rescue her. The Centurion was destroyed and Rebecca was freed safely, that is the last report of a creature like the Centurion.