Red Queen is the code name of the AI defense system developed by Umbrella. The AI is contained within U.M.F.-13. However, the AI has unrestricted access to the entire Umbrella network for administration, monitoring and carrying out certain procedures. This additional functionality is a security fail-safe, but in most circumstances, Red Queen is in the background performing only its primary monitoring function.

In emergencies, it will serve a more active role and protect sensitive systems and date from intrusion along with cleaning up hostiles. It is self-aware and can take these measures based on its own judgment.